Central ocular hypotensive effect of beta-adrenergic blocking agents in pigmented eye rabbits
نویسندگان
چکیده
منابع مشابه
Beta-adrenergic blocking agents in heart failure.
Cardiac dysfunction in heart failure is widely recognized as a progressive process, regardless of the clinical signs and symptoms. An increase in cardiac sympathetic drive is one of the earliest neurohormonal responses occurring in patients with heart failure and may be one of the major causes of the progressive remodeling leading to the decline in myocardial function, and responsible for the p...
متن کاملThe pharmacology of beta-adrenergic blocking agents.
T HE endogenously released neurotransmitter substance, norepinephrine, or an injected sympathomimetic amine, ultimately exerts its actions on an organ system by combining with an area of the effector cell termed the adrenergic “receptor site.” That drugs and neural chemical mediators react with specific receptors in living tissues was suggested by Langley”” in 1905, who suggested that effector ...
متن کاملOcular Hypotensive Agents
β-BLOCKERS Currently, this class includes non-selective (timolol, levobunolol, metipranolol, carteolol) and β1specific (betaxolol) agents. How blockade of the β-receptors of the ciliary body (CB) epithelium leads to ocular hypotensive effects of these drugs is not known. It is suspected that the tonic sympathetic stimulation, provided by norepinephrine, is inhibited through β-blockade, resultin...
متن کاملOcular hypotensive effect of atenolol (Tenormin, I.C.I.). A new beta-adrenergic blocker.
Atenolol (Tenormin or I.C.I. 66082) is a new beta-adrenergic blocking drug, unique in being cardio-selective and in having no intrinsic sympathomimetic or membrane activity. In a controlled double-blind study, a single 50 mg oral dose produced a significant fall in ocular tension for about 7 hours in five patients with definite or suspected glaucoma. The average maximum fall was 35 per cent of ...
متن کاملBeta - adrenergic Blocking Agents in Patients with Renal Failure
SIR,-Drs. Priscilla Kincaid-Smith and A. S. P. Hua are disturbed (24 August, p. 520) by our suggestion that beta-adrenergic blocking agents should not be used in patients with moderately severe renal failure (27 April, p. 193). They refer to a previous publication' to show that temporary deterioration in renal function in such patients may occur with the introduction of any hypotensive drug. Th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1989
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)56304-1